Tissue Cobalt Content and Excretion in Mice and Rats Following Injection of Cobalt Chloride
نویسندگان
چکیده
منابع مشابه
Cobalt Chloride Treatment and Iron Metabolism in Immature Mice
Although cobalt is an essential trace element, it is toxic in high concentrations. Long-term exposure to cobalt chloride (CoCl2) significantly increases Co(II) ions in blood serum, spleen and liver of treated immature mice compared to controls and induces changes in the iron (Fe) content. Spleen and liver show different sensitivity to Co(II) administration but increase iron storage. The three e...
متن کاملdetermination of olanzapine and thiourea using electrodes modified by dna and film of copper-cobalt hexacyanoferrate & investigation of electro-oxidation of some catechol derivatives in the presence of 4-phenylsemicarbazid
چکیده هدف از این کار بررسی الکترواکسیداسیون کتکول و مشتقات آن در حضور 4-فنیل سمی کاربامازید بوده است اکسیداسیون کتکولها ترکیبات نا پایدار کینونها را تولید می کنند که این ترکیبات می تواند در واکنش مایکل بعنوان پذیرنده نوکلئوفیل عمل نمایند. در ادامه اکسایش کتکولهای (a-c1) را درحضور 4-فنیل سمی کاربامازید در محلول آب/استونیتریل (90/10)بوسیله ولتامتری چرخه ای و کولن متری در پتانسیل ثابت مورد بررسی ...
15 صفحه اولEffects of cobalt chloride, nickel chloride, and nickel subsulfide upon erythropoiesis in rats.
The erythropoietic effects of sustained intraperitoneal (i.p.) administration of CoCl2 and NiCl2 were compared with the effects of a single intrarenal (i.r.) injection of alpha Ni3S2 in female Fischer-344 rats. Infusion of NiCl2 by osmotic minipumps (0.85 mg Ni per day, i.p., for 24 days; total dose = 20 mg Ni per rat) did not alter the blood hematocrit or reticulocyte count during six weeks of...
متن کاملPreconditioning with cobalt chloride modifies pain perception in mice
Cobalt chloride (CoCl2) modifies mitochondrial permeability and has a hypoxic-mimetic effect; thus, the compound induces tolerance to ischemia and increases resistance to a number of injury types. The aim of the present study was to investigate the effects of CoCl2 hypoxic preconditioning for three weeks on thermonociception, somatic and visceral inflammatory pain, locomotor activity and coordi...
متن کاملP-122: Effects of Cobalt Chloride and Chromium Chloride on Development of Mouse Testes
Background: Cobalt (Co) is an essential trace element for mammals required for the synthesis of vitamin B12. It is not a cumulative toxin but chronic exposure induces negative effects on the organism. It was proven that cobalt passes via placenta appearing in the fetal blood and amniotic fluid and it is shown to possess an embryotoxic effect. Also, chromium (Cr) is recognized as a trace element...
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ژورنال
عنوان ژورنال: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)
سال: 1974
ISSN: 0021-5082,1882-6482
DOI: 10.1265/jjh.29.289